Jitsi backend can accept multiple issuers and application ids

Hello,
We have a laravel web application that is used as a frontend for the jitsi backend with working JWT authentification so my question is can the jitsi backend accept multiple issuers and application ids?
we are trying to connect two application to the same jitsi backend
keep in mind that this whole application is deployed via docker-compose
also there is these two option
# (Optional) Set asap_accepted_issuers as a comma separated list
#JWT_ACCEPTED_ISSUERS=my_web_client,my_app_client

# (Optional) Set asap_accepted_audiences as a comma separated list
#JWT_ACCEPTED_AUDIENCES=my_server1,my_server2
what are the purpose of them ? do i need to add the domain of the other application that needs to connect to the backend ??
thank you