ERR_EMPTY_RESPONSE returned for some users

Screen Shot 20200516 at 12.06.19 AM

We are facing this error for some users, I am attaching logs along with this

2020/05/15 05:42:29 [error] 415#415: *2006745 recv() failed (104: Connection reset by peer) while proxying and reading from upstream, client: 223.185.41.140, server: 0.0.0.0:443, upstream: “127.0.0.1:4445”, bytes from/to client:0/0, bytes from/to upstream:0/450

prosody version - 0.11.5-1~bionic6
jicofo 1.0-541-1
jitsi-videobridge2 2.1-164-gfdce823f-1
Nginx 1.14.0-0ubuntu1.7

@damencho please help on this one.